Theses - Publications

in peer-review Scientific Journals

Theses

  1. PhD Thesis
    “Isohexenylnaphthazarins: Chemistry – Technology – Biology”

    Organic Chemistry Laboratory, School of Chemical Engineering, AUTh, Supervisor: Professor V.P. Papageorgiou.
    (December 1997-July 2001)

  2. Diploma Thesis
    “Technoeconomic study for the industrial production of the wound healing ointment HELIXDERM®, and production of pharmaceutical and cosmetic formulations”
    Organic Chemistry Laboratory, School of Chemical Engineering, AUTh, Supervisor: Professor V.P. Papageorgiou.

  3. MSc Diploma Thesis
    “Production planning and inventory management for the industry of canned finished foods of ZANAE”.

    ZANAE industrial plant, in cooperation with the Director of the Factory, Mr. G. Intzes.
    (June-November 1999)

Publications

  1. V.P. Papageorgiou, A.N. Assimopoulou, E.A. Couladouros, D. Hepworth and K.C. Nicolaou: “The Chemistry and Biology of Alkannin, Shikonin and Related Naphthazarin Natural Products”, Review article, Angewandte Chemie, Int. Edition, 38(3), 270-300 (1999).
    – P. Papageorgiou, A.N. Assimopoulou, E.A. Couladouros, D. Hepworth and K.C. Nicolaou: “Chemie und Biologie von Alkannin, Shikonin und verwandten Naphthazarin-Naturstoffen”, Angewandte Chemie, 111(3), 280-311 (1999).
  2. V.P. Papageorgiou, A.S. Mellidis, A.N. Assimopoulou and A. Tsarbopoulos: “Use of Matrix-assisted Laser desorption/ionization Mass Spectrometry for the Rapid Detection of Low-Mass Components in the Alkanna tinctoria pigments’ fraction”, Journal of Mass Spectrometry, 33, 89-91 (1998).
  3. Ζ.F. Plyta, T. Li, V. P. Papageorgiou, A. S. Mellidis, A. N. Assimopoulou, E.N. Pitsinos, E. A. Couladouros: “Inhibition of topoisomerase I by naphthaquinone derivatives”, Bioorganic & Medicinal Chemistry Letters, 8, 3385-3390 (1998).
  4. V.P. Papageorgiou, A.N. Assimopoulou and N. Yannovits-Argiriadis: “Chemical composition of the essential oil of Chios turpentine”, Journal of Essential Oil Research, 11, 367-368, (1999).
  5. V.P. Papageorgiou, A.N. Assimopoulou and G. Kyriacou: “Determination of naturally occurring hydroxynaphthoquinone polymers by Size Exclusion Chromatography”, Chromatographia, 55 (7/8), 423-430 (2002).
  6. Ν.K. Andrikopoulos, A.C. Kaliora, A.N. Assimopoulou, V.P. Papageorgiou: “Inhibitory activity of minor polyphenolic and nonpolyphenolic constituents of olive oil against in vitro Low-Density Lipoprotein oxidation”, Journal of Medicinal Food, 5(1), 1-7 (2002).
  7. Ν.K. Andrikopoulos, A.C. Kaliora, A.N. Assimopoulou, V.P. Papageorgiou: “Biological activity of some naturally occurring resins, gums and pigments against in vitro LDL oxidation”, Phytotherapy Research, 17(5), 501-507 (2003).
  8. Α.P. Kourounakis, A.N. Assimopoulou, V.P. Papageorgiou, A. Gavalas, P.N. Kourounakis: “Alkannin and Shikonin: Effect on free radical processes and on inflammation. A preliminary pharmacochemical investigation”, Arch. Pharm. Pharm. Med. Chem., 335(6), 262-266 (2002).
  9. Ν.K. Andrikopoulos, A.C. Kaliora, A.N. Assimopoulou, V.P. Papageorgiou: “Biological activity of saliva against in vitro LDL oxidation after chewing commercial chewing gums”, Italian Journal of Food Science, 14 (3), 279-289 (2002).
  10. V.P. Papageorgiou, A.N. Assimopoulou: “Lipids of the hexane extract from the roots of medicinal Boraginaceous species”, Phytochemical Analysis, 14, 251-258 (2003).
  11. A.N. Assimopoulou, V.P. Papageorgiou and K.C. Kiparissides: “Synthesis and release studies of shikonin-containing microcapsules prepared by the solvent evaporation method”, J. Microencapsulation, Sep-Oct, 20(5), 581-596 (2003).
  12. A.N. Assimopoulou, V.P. Papageorgiou: “Encapsulation of isohexenyl-naphthazarins in cyclodextrins”, Biomedical Chromatography, 18, 240-247 (2004).
  13. A.N. Assimopoulou, V.P. Papageorgiou: “Study on polymerization of the pharmaceutical substances isohexenylnaphthazarins”, Biomedical Chromatography, 18(8), 492-500 (2004).
  14. A.N. Assimopoulou, V.P. Papageorgiou: “Preparation and release studies of alkannin-containing microcapsules”, J. Microencapsulation, 21(2), 161-173 (2004).
  15. A.N. Assimopoulou, V.P. Papageorgiou: “Study on isohexenylnaphthazarins polymerization in alkaline media”, Biomedical Chromatography, 18(8), 508-522 (2004).
  16. Α.N. Assimopoulou, V.P. Papageorgiou: “Study on the enantiomeric ratio of the pharmaceutical substances alkannin and shikonin”, Biomedical Chromatography, 18(8), 791-799 (2004).
  17. A.N. Assimopoulou, D. Boskou, V.P. Papageorgiou: “Antioxidant activities of alkannin, shikonin and Alkanna tinctoria root extracts in oil substrates”, Food Chemistry, 87, 433-438 (2004).
  18. Α.N. Assimopoulou, S.N. Zlatanos, V.P. Papageorgiou: “Antioxidant activity of natural resins and bioactive triterpenes in oil substrates”, Food Chemistry, 92, 721-727 (2005).
  19. Μ.A. Anagnostopoulou, P. Kefalas, V.P. Papageorgiou, A.N. Assimopoulou, D. Boskou: “Radical scavenging activity of various extracts and fractions of sweet orange peel (Citrus sinensis)”, Food Chemistry, 94 (1), 19-25 (2006).
  20. Μ.A. Anagnostopoulou, P. Kefalas, E. Kokkalou, A.N. Assimopoulou, V.P. Papageorgiou: “Analysis of antioxidant compounds in sweet orange peel by HPLC-diode array detection-electrospray ionization mass spectrometry”, Biomedical Chromatography, 19(2), 138-148 (2005).
  21. A.N. Assimopoulou and V.P. Papageorgiou: “GC-MS analysis of penta- and tetra-cyclic triterpenes from resins of Pistacia species. Part I. Pistacia lentiscus var. Chia”, Biomedical Chromatography, 19, 285-311 (2005).
  22. A.N. Assimopoulou and V.P. Papageorgiou: “GC-MS analysis of penta- and tetra-cyclic triterpenes from resins of Pistacia species. Part II. Pistacia terebinthus var. Chia”, Biomedical Chromatography. 19, 586-605 (2005).
  23. Spyros, A.N. Assimopoulou, V.P. Papageorgiou: “Structure determination of oligomeric alkannin and shikonin derivatives”, Biomedical Chromatography, 19, 498-505 (2005).
  24. Α.N. Assimopoulou,P. Papageorgiou: “Radical scavenging activity of Alkanna tinctoria root extracts and their main constituents, hydroxynaphthoquinones”, Phytotherapy Research, 19(2), 141-147 (2005).
  25. A.N. Assimopoulou, Z. Sinakos, V.P. Papageorgiou: “Radical scavenging activity of Crocus sativus L. extract and its bioactive constituents”, Phytotherapy Research, 19, 997-1000 (2005).
  26. V.P. Papageorgiou, A.N. Assimopoulou, V.F. Samanidou, I.N. Papadoyannis: “Analytical methods for the determination of alkannins and shikonins”, Invited review article, Current Organic Chemistry, 10(5), 583-622 (2006).
  27. V.P. Papageorgiou, A.N. Assimopoulou, V.F. Samanidou, I.N. Papadoyannis: “Recent advances in chemistry, biology and biotechnology of alkannins and shikonins”, Invited review article, Current Organic Chemistry, 10(16), 2123-2142 (2006).
  28. A.N. Assimopoulou, I. Karapanagiotis, A. Vasiliou, S. Kokkini, V.P. Papageorgiou: “Analysis of alkannin derivatives from Alkanna species by high-performance liquid chromatography/photodiode array/mass spectrometry”, Biomedical Chromatography, 20, 1359-1374 (2006).
  29. A.N. Assimopoulou, V.P. Papageorgiou: “Oleoresins from Pistacia species: Chemistry and Biology”, Recent progress in Medicinal Plants, Natural Products II, Vol.18, CΗ 7: Common and chronic diseases, p.146-202, Studium Press LLC, USA, (2007).
  30. Α.Ν. Assimopoulou, M. Ganzera, Η. Stuppner, V.P. Papageorgiou: “Simultaneous determination of monomeric and oligomeric alkannins and shikonins by high-performance liquid chromatography-diode array detection-mass spectrometry”, Biomedical Chromatography, 22(2), 173-190 (2008).
  31. Α.Ν. Assimopoulou, S. Sturm, Η. Stuppner, V.P. Papageorgiou: “Preparative isolation and purification of alkannin/shikonin derivatives from natural products by High-Speed Counter-Current Chromatography”, Biomedical Chromatography, 23, 182-198 (2009).
  32. V.P. Papageorgiou, A.N. Assimopoulou, A.C. Ballis: “Alkannins and Shikonins: A New Class of wound healing agents”, Invited review article, Current Medicinal Chemistry, 15(30), 3248-3267 (2008).
  33. Maria Karayannopoulou, Panagiotis Loukopoulos, Lysimachos G. Papazoglou, Vassiliki Tsioli, Tilemahos Anagnostou, Nikolaos Assaloumidis, Theodoros C. Constantinidis, Andreana N. Assimopoulou, Eleni Kaldrymidou and Vassilios P. Papageorgiou: “Naturally occurring isohexenylnaphthazarins and wound healing: experimental study in dogs”, Journal of Cutaneous Medicine & Surgery, 14 (2), 62-70 (2010).
  34. E. Noula, V.F. Samanidou, A.N. Assimopoulou, V.P. Papageorgiou, I.N. Papadoyannis: “Solid-phase extraction for purification of alkannin/shikonin samples and isolation of monomeric and dimeric fractions”, Analytical and Bioanalytical Chemistry, 397, 2221–2232 (2010).
  35. Stella A. Ordoudi, Stella K. Tsermentseli, Nikolaos Nenadis, Andreana N. Assimopoulou, Maria Z. Tsimidou, Vassilios P. Papageorgiou: “Structure-radical scavenging activity relationship of alkannin/shikonin derivatives”, Food Chemistry, 124(1), 171-176 (2011).
  36. Rasmus K. Petersen, Kathrine B. Christensen, Andreana N. Assimopoulou, Xavier Fretté, Vassilios P. Papageorgiou, Karsten Kristiansen and Irene Kouskoumvekaki: “Pharmacophore-driven identification of PPARγ agonists from natural sources”, Journal of Computer-Aided Molecular Design, 25(2), 107-116, February (2011).
  37. Konstantinos N. Kontogiannopoulos, Andreana N. Assimopoulou, Ioannis Tsivintzelis, Costas Panayiotou, Vassilios P. Papageorgiou: “Electrospun fiber mats containing shikonin and derivatives with potential biomedical applications”, International Journal of Pharmaceutics, 409(1-2), 216-228 (2011).
  38. Konstantinos N. Kontogiannopoulos, Andreana N. Assimopoulou, Konstantinos Dimas, Vassilios P. Papageorgiou. “Shikonin–loaded liposomes as a new drug delivery system: Physicochemical characterization and in vitro cytotoxicity”, European Journal of Lipid Science and Technology, 113, 1113–1123 (2011).
  39. I. Tanis, K. Karatasos, A.N. Assimopoulou, V.P. Papageorgiou: “Modeling of hyperbranched polyesters as hosts for the multifunctional bioactive agent shikonin”, Physical Chemistry Chemical Physics,13, 10808-10817 (2011).
  40. Ahmad Ali, Andreana N. Assimopoulou, Vassilios P. Papageorgiou, Herbert Kolodziej: “Structure/Antileishmanial activity relationship study of naphthoquinones and dependency of the mode of action on the substitution patterns”, Planta Medica, 77 (18) 2003-2012 (2011).
  41. Konstantinos N. Kontogiannopoulos, Andreana N. Assimopoulou, Sophia Hatziantoniou, Kostas Karatasos, Costas Demetzos, Vassilios P. Papageorgiou: “Chimeric advanced drug delivery nano systems (chi-aDDnSs) for shikonin combining dendritic and liposomal technology”, International Journal of Pharmaceutics, 422(1-2), 381-389 (2012).
  42. S.K. Tsermentseli, P. Manesiotis, A.N.Assimopoulou, V.P.Papageorgiou: “Molecularly imprinted polymers for the isolation of bioactive naphthoquinones from plant extracts”, Journal of Chromatography A, 1315, 15–20 (2013).
  43. Jasmin Tappeiner, Alexandra Vasiliou, Markus Ganzera, Dimitrios Fessas, Hermann Stuppner, Vassilios P. Papageorgiou, Andreana N. Assimopoulou: “Quantitative determination of alkannins and shikonins in endemic Mediterranean Alkanna species”, Biomedical Chromatography, 28(7),923–933 (2014).
  44. K.N. Kontogiannopoulos, S.K. Tsermentseli, A.N. Assimopoulou, V.P. Papageorgiou. “Sterically stabilized liposomes as a potent carrier for Shikonin”, J. Liposome Research, Sep; 24(3): 230-240 (2014).
  45. Anna Vuorinen, Julia Seibert, Vassilios P. Papageorgiou, Judith M. Rollinger, Alex Odermatt, Daniela Schuster, Andreana N. Assimopoulou: “Pistacia lentiscus oleoresin: virtual screening and identification of masticadienonic and isomasticadienonic acids as inhibitors of 11β-hydroxysteroid dehydrogenase 1”. Planta Medica special issue dedicated to “In silico driven pharmacognosy: forth, back and reverse”. Invited paper, Planta Med, 81(06): 525-532 (2015).
  46. Qiaoli Zhao, Andreana N. Assimopoulou, Sabine M. Klauck, Harilaos Damianakos, Ioanna Chinou, Nadine Kretschmer, José-Luis Rios, Vassilios P. Papageorgiou, Rudolf Bauer, Thomas Efferth: “Inhibition of c-MYC with involvement of ERK/JNK/MAPK and AKT pathways as a novel mechanism for shikonin and its derivatives in killing leukemia cells”, Oncotarget, 6(36), 38934-38951 (2015).
  47. E.G. Karapanagioti, A.N. Assimopoulou: “Naturally occurring wound healing agents: An evidence-based review”, Current Medicinal Chemistry, 23(29): 3285-3321 (2016).
  48. E.D. Spyrelli, A.V. Kyriazou, C. Virgiliou, A. Nakas, O. Deda, V.P. Papageorgiou, A.N. Assimopoulou and H.G. Gika: “Metabolic profiling study of shikonin’s cytotoxic activity in the Huh7 human hepatoma cell line”, Molecular BioSystems, May 2;13(5):841-851 (2017).
  49. Stella K. Tsermentseli, Konstantinos N. Kontogiannopoulos, Vassilios P. Papageorgiou, Andreana N. Assimopoulou: “Comparative study of pegylated and conventional liposomes as carriers for shikonin”, Fluids -Special Issue Experimental and Numerical Studies in Biomedical Engineering, 3, 36 (2018).
  50. Konstantinos N. Kontogiannopoulos, Athanasia Dasargyri, Maria F. Ottaviani, Michela Cangiotti, Dimitrios Fessas, Vassilios P. Papageorgiou, Andreana N. Assimopoulou: “Advanced drug delivery nanosystems for shikonin: A calorimetric and Electron Paramagnetic Resonance study”, Langmuir, 34 (32), pp 9424–9434 (2018).
  51. Koletti, A.E., Tsarouchi, E., Kapourani, A., Kontogiannopoulos, K.N., Assimopoulou, A.N., Barmpalexis, P: “Gelatin nanoparticles for NSAID systemic administration: Quality by design and artificial neural networks implementation”, International journal of pharmaceutics, 578, 119118, (2020). (click here to view the paper).
  52. Papadaki, E., Kontogiannopoulos, K.N., Assimopoulou, A.N. & Mantzouridou, F. T. Feasibility of multi-hydrolytic enzymes production from optimized grape pomace residues and wheat bran mixture using Aspergillus niger in an integrated citric acid-enzymes production process. Bioresource Technology, 123317, (2020).
  53. Nakas, A., Dalatsi, A.M., Kapourani, A., Kontogiannopoulos, K.N., Assimopoulou, A.N., Barmpalexis, P., Quality Risk Management and Quality by Design for the Development of Diclofenac Sodium Intra-articular Gelatin Microspheres, AAPS PharmSciTech, 21 (4), 127, (2020).
  54. Loukri, A., Tsitlakidou, P., Goula, A., Assimopoulou, A.N., Kontogiannopoulos, K.N., Mourtzinos, I., Green Extracts from Coffee Pulp and Their Application in the Development of Innovative Brews, Applied Sciences, 10 (19), 6982, (2020).
  55. Mouskeftara, T., Goulas, A., Ioannidou, D., Ntenti, C., Agapakis, D., Assimopoulou, A., Gika, H., A study of blood fatty acids profile in hyperlipidemic and normolipidemic subjects in association with common pnpla3 and abcb1 polymorphisms, Metabolites, 11 (2), 1-15, (2021)
  56. Rat, A., Naranjo, H.D., Krigas, N., Grigoriadou, K., Maloupa, E., Alonso, A.V., Schneider, C., Papageorgiou, V.P., Assimopoulou, A.N., Tsafantakis, N., Fokialakis, N., Willems, A. Endophytic Bacteria From the Roots of the Medicinal Plant Alkanna tinctoria Tausch (Boraginaceae): Exploration of Plant Growth Promoting Properties and Potential Role in the Production of Plant Secondary Metabolites, Frontiers in Microbiology, 12, 113, (2021).
  57. Arampatzis, A.S., Giannakoula, K., Kontogiannopoulos, K.N., Theodoridis, K., Aggelidou, E., Rat, A., Kampasakali, E., Willems, A., Christofilos, D., Kritis, A., Papageorgiou, V.P., Tsivintzelis, I., Assimopoulou, A.N., Novel electrospun poly-hydroxybutyrate scaffolds as carriers for the wound healing agents alkannins and shikonins, Regenerative Biomaterials, 8 (3), (2021).
  58. Virgiliou, C., Zisi, C., Kontogiannopoulos, K.N., Nakas, A., Iakovakis, A., Varsamis, V., Gika, H.G., Assimopoulou, A.N., Headspace gas chromatography-mass spectrometry in the analysis of lavender’s essential oil: Optimization by response surface methodology, Journal of Chromatography B, 1179, 122852, (2021).
  59. Arampatzis, A.S., Kontogiannopoulos, K.N., Theodoridis, K., Aggelidou, E., Rat, A., Willems, A., Tsivintzelis, I., Papageorgiou, V.P., Kritis, A., Assimopoulou, A.N., Electrospun wound dressings containing bioactive natural products: physico-chemical characterization and biological assessment, Biomaterials Research, 25 (1), 23, (2021).
  60. Spent coffee grounds’ valorization towards the recovery of caffeine and chlorogenic acid: A response surface methodology approach, Mitraka, G.-C., Kontogiannopoulos, K.N., Batsioula, M., Banias, G.F., Assimopoulou, A.N., Sustainability (Switzerland), 13(16), 8818 (2021)
  61. Chrysa Anagnostopoulou, Konstantinos N. Kontogiannopoulos, Maria Gaspari, Maria Silvia Morlino, Andreana N. Assimopoulou, Panagiotis G. Kougias, Valorization of household food wastes to lactic acid production: A response surface methodology approach to optimize fermentation process, Chemosphere, (2022), https://doi.org/10.1016/j.chemosphere.2022.133871.

  62.   Afroditi Kapourani, Konstantinos N. Kontogiannopoulos, Alexandra-Eleftheria Manioudaki, Athanasios K. Poulopoulos, Lazaros Tsalikis, Andreana N. Assimopoulou, Panagiotis Barmpalexis*. Management approaches and the role of advanced polymeric materials in the treatment of xerostomia: a systematic review, 2022, Polymers, 14, 850,  https://doi.org/10.3390/polym14050850 If: 4.329 (2020). 

  63.  Athanasios S Arampatzis, Olga Tsave, Benjamin Kirchweger, Julia Zwirchmayr, Vassilios P Papageorgiou, Judith Maria Rollinger,
    Andreana N Assimopoulou, “Expanding the biological properties of alkannins and shikonins: A two model-systems approach”,     Front. Pharmacol. 13:909285. 2022. doi: 10.3389/fphar.2022.909285 If 5.811  

  64.   Velliadou D., Antoniadis K.D., Assimopoulou A.N., Assael M.J., and Wakeham W.A., “Accurate Measurements of the Thermal Conductivity of Hexadecan-1-ol and Octadecan-1-ol in the Solid and Liquid Phases “, Int. J. Thermophys. (2022) 43:124, https://doi.org/10.1007/s10765-022-03049-2. If 1.608

  1. Cintia Csorba, Nebojsa Rodic, Yanyan Zhao, Livio Antonielli, Günter Brader, Angeliki Vlachou, Evangelia Tsiokanos, Ismahen Lalaymia, Stéphane Declerck, Vassilios Papageorgiou, Andreana N. Assimopoulou and Angela Sessitsch. Metabolite production in Alkanna tinctoria links plant development with the recruitment of individual members of microbiome thriving at the root-soil interface, mSystems 2022 Sep 7;e0045122.doi: 10.1128/msystems.00451-22; if (2021) 7.331, June 2022
  2. AliciaVarela Alonso, Henry D. Naranjo, Angélique Rat, Nebojša Rodić, Christina I. Nannou, Dimitra A Lambropoulou, Andreana N Assimopoulou, Stéphane Declerck, Philipp Rödel, Carolin Schneider, and Anne Willems. Root-associated bacteria modulate the specialised metabolome of Lithospermum officinale Front. Plant Sci. 13:908669. doi: 10.3389/fpls.2022.908669, 2022, if (2021) 6.627
  3. Muhammad Ahmad, Alicia Varela Alonso, Antigoni E. Koletti, Andreana N. Assimopoulou, Stéphane Declerck, Carolin Schneider and Eva M. Molin. Transcriptional dynamics of Chitinophaga strain R-73072-mediated alkannin/shikonin biosynthesis in Lithospermum officinale, Front. Microbiol 13:978021. doi: 10.3389/fmicb.2022.978021; if (2021) 6.064, July 2022 (section Microbe and Virus Interactions with Plants)
  4. Maria Koromili, Afroditi Kapourani, Antigoni E. Koletti, George Papandreou, Andreana N Assimopoulou, Diamanto Lazari and Panagiotis Barmpalexis. Preparation and evaluation of siderolamorphous solid dispersions: selection of suitable matrix/carrier, AAPS PharmSciTech, 2022, Aug 3;23(6):214, doi: 10.1208/s12249-022-02368-9; if (2021) 4.026.
  5. Antigoni E. Koletti, Konstantinos N. Kontogiannopoulos, Konstantinos Gardikis, Sophia Letsiou, Vassilios P. Papageorgiou, Andreana N. Assimopoulou*. Nanostructured lipid carriers of alkannins and shikonins: Experimental Design, Characterization and bioactivity studies. Ιnvited paper, revision submitted, Journal of Drug Delivery Science & Technology, July 2022; if (2021) 062
  6. Chatzopoulos, Georgios S., Panagiotis Karakostas, Stefania Kavakloglou, Andreana Assimopoulou, Panagiotis Barmpalexis, and Lazaros Tsalikis. 2022. “Clinical Effectiveness of Herbal Oral Care Products in Periodontitis Patients: A Systematic Review” International Journal of Environmental Research and Public Health19, 2022, 19 no. 16: 10061. https://doi.org/10.3390/ijerph191610061, if (2021): 4.614
  7. Angélique Rat, Antigoni E Koletti, Nebojša Rodić, Vassilis Papageorgiou, Anne Willems , Andreana N Assimopoulou. Bacterial responses to plant antimicrobials: the case of alkannin and shikonin derivatives. (2023) Frontiers in Pharmacology, 14, art. no. 1244270, DOI: 10.3389/fphar.2023.1244270

  8. Afroditi Kapourani, Katerina Kirimkiroglou,  Konstantina Chachlioutaki,  Maria Koromili, Christos Ritzoulis, Andreana N. Assimopoulou, Dimitrios A. Andreadis,  Dimitrios G. Fatouros, Panagiotis Barmpalexis. Evaluation of pilocarpine in situ forming buccal gels as potential formulations for the management of xerostomia,   Journal of Drug Delivery Science and Technology. Volume 86, September 2023, 104698

  9. Kontogiannopoulos, K.N.; Kapourani, A.; Gkougkourelas, I.; Anagnostaki, M.-E.; Tsalikis, L.; Assimopoulou, A.N.; Barmpalexis, P. A Review of the Role of Natural Products as Treatment Approaches for Xerostomia. Pharmaceuticals 2023, 16, 1136. https://doi.org/10.3390/ ph16081136

  10. Vasiliki Valkanioti, Afroditi Kapourani, Melina Chatzitheodoridou, Maria-Emmanouela Anagnostaki, Ioannis Gkougkourelas, Konstantinos N. Kontogiannopoulos, Andreana N. Assimopoulou, Panagiotis Barmpalexis. Carbopol coated mucoadhesive PLGA nanoparticles for the sustained delivery of pilocarpine in the buccal cavity. RPS Pharmacy and Pharmacology Reports, Volume 2, Issue 3, May 2023, rqad024, https://doi.org/10.1093/rpsppr/rqad024

  11. Goutzourelas N, Kevrekidis DP, Barda S, Malea P, Trachana V, Savvidi S, Kevrekidou A, Assimopoulou AN, Goutas A, Liu M, Lin X, Kollatos N, Amoutzias GD, Stagos D. Antioxidant Activity and Inhibition of Liver Cancer Cells’ Growth of Extracts from 14 Marine Macroalgae Species of the Mediterranean Sea. Foods. 2023 Mar 19;12(6):1310. doi: 10.3390/foods12061310. 
  12. Marinaki, Maria, Ioannis Sampsonidis, Alexandros Nakas, Panagiotis Arapitsas, Andreana N. Assimopoulou, and Georgios Theodoridis. 2023. “Analysis of the Volatile Organic Compound Fingerprint of Greek Grape Marc Spirits of Various Origins and Traditional Production Styles” Beverages 9, no. 3: 65. https://doi.org/10.3390/beverages9030065

  13. Muhammad Ahmad, Alicia Varela Alonso, Antigoni E. Koletti, Nebojša Rodić, Michael Reichelt, Philipp Rödel, Andreana N. Assimopoulou, Ovidiu Paun, Stéphane Declerck, Carolin Schneider, and Eva M. Molin. Dynamics of alkannin/shikonin biosynthesis in response to jasmonate and salicylic acid in Lithospermum officinale. Scientific Reports; 12, 17093 September 2022; if (2021) 4.996. https://doi.org/10.1038/s41598-022-21322-0

  14.  Dimitrios Mertzanidis, Alexandros Nakas, Andreana N. Assimopoulou, Stella Kokkini. Unravelling the chemotaxonomic identity of “white” and “black” oregano (Origanum vulgare) in Northern Greece.  Planta Med. 2023 Apr;89(4):433-440. doi: 10.1055/a-1949-8895.

  15. Danai Velliadou  · Konstantinos D. Antoniadis  · Andreana N. Assimopoulou  · Marc J. Assael  ·Maria Carolina Margarido Sequeira  ·
    William A. Wakeham. Accurate Measurements of the Thermal Conductivity of n-Docosane, n-Tetracosane, 1,6-Hexanediol, and 1,8-Octanediol in the Solid and Liquid Phases.     Int J Thermophys 44, 78 (2023). https://doi.org/10.1007/s10765-023-03182-6

  16. Theodoridis K, Arampatzis A, Liasi G, Tsalikis L, Barmpalexis P,  Christofilos D, Assimopoulou A. 3D-Printed Antibacterial Scaffolds for the
    Regeneration of Alveolar Bone in Severe Periodontitis. International Journal of Molecular Sciences. 2023.     24(23), 16754; 
    https://doi.org/10.3390/ijms242316754  

  17. Arampatzis, A.S.; Pampori, A.; Droutsa, E.; Laskari, M.; Karakostas, P.; Tsalikis, L.; Barmpalexis, P.; Dordas, C.; Assimopoulou, A.N. Occurrence of Luteolin in the Greek Flora, Isolation of Luteolin and Its Action for the Treatment of Periodontal Diseases.
    Molecules 2023, 28, 7720.     https://doi.org/10.3390/molecules28237720

  18. Alvanoudi, P., Ordoudi, S.A., Nakas, A. , A.N. Assimopoulou, F.Th. Mantzouridou. Brine Volatilome Changes Along the Spontaneous Fermentation of Spanish-Style cv. Chalkidiki Green Olives Under High and Low NaCl Conditions. Food Bioprocess Technol (2023). https://doi.org/10.1007/s11947-023-03211-0

  19. Kampasakali, E; Nakas, A; Mertzanidis, D; Kokkini, S; Assimopoulou, AN; Christofilos D.,  μ-Raman Determination of Essential Oils’ Constituents from Distillates and Leaf Glands of Origanum Plants, Molecules, 2023, 28, 1221.

  20.  Optimizing the distillation of Greek oregano – Do process parameters affect bioactive aroma constituents and in vitro antioxidant
    activity?, Nakas A, Giannarelli G, Fotopoulos I, Chainoglou E, Peperidou A, Kontogiannopoulos KN, Tsiaprazi-Stamou A, Varsamis V, Gika HG, Hadjipavlou-Litina D, Assimopoulou AN . Molecules 2023, 28(3), 971,     doi: 10.3390/molecules28030971

  21. Davidopoulou, S.; Batas, L.; Karakostas, P.; Tortopidis, D.; Barmpalexis, P.; Assimopoulou, A.; Angelopoulos, C.; Tsalikis, L. Multidimensional 3D-Printed Scaffolds for Ridge Preservation and Dental Implant Placement: A Systematic Review. Appl. Sci. 2024, 14, 892. https://doi.org/10.3390/app14020892

  22. Davidopoulou, S.; Karakostas, P.; Batas, L.; Barmpalexis, P.; Assimopoulou, A.; Angelopoulos, C.; Tsalikis, L. Multidimensional 3D-Printed Scaffolds and Regeneration of Intrabony Periodontal Defects: A Systematic Review. J. Funct. Biomater. 2024, 15, 44. https://doi.org/10.3390/jfb15020044

  23. Verykokou, S.; Ioannidis, C.; Soile, S.; Angelopoulos, C.; Theodoridis, K.; Arampatzis, A.S.; Assimopoulou, A.N.; Christofilos, D.; Kapourani, A.; Pantazos, I.; Barmpalexis, P. Boutsi, A-M. and Chryssy Potsiou. The Role of Cone Beam Computed Tomography in Periodontology: From 3D Models of Periodontal Defects to 3D-Printed Scaffolds. J. Pers. Med. 2024, 14, 207. https://doi.org/10.3390/jpm14020207

  24. Yanyan Zhao, Nebojša Rodić, Marios Liaskos, Andreana N. Assimopoulou, Ismahen Lalaymia, Stéphane Declerck, Effects of fungal endophytes and arbuscular mycorrhizal fungi on growth of Echium vulgare and alkannin/shikonin and their derivatives production in roots, Fungal Biology, Volume 128, Issue 1, 2024, 1607-1615,  https://doi.org/10.1016/j.funbio.2023.12.004

        

 

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